Laboratory Animal Allergens

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Laboratory animal allergens.

Allergic sensitivity to laboratory animals can pose a significant occupational hazard to anyone with regular animal contact. Reactions to mice and rats are most common although all furred animals produce allergens that can lead to sensitization and disease. Most of the relevant allergens of laboratory animals have been defined and characterized, which has revealed that these allergens are typic...

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Controlling exposure to laboratory animal allergens.

Laboratory animal allergy (LAA) is a significant occupational disease that may affect up to one third of personnel exposed to laboratory animals. Research has characterized the relative risks of exposure, in terms of intensity, frequency, and duration, associated with given tasks and work areas in the animal facility. Studies have shown that reduced exposure to animal allergens can reduce the i...

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Spreading of occupational allergens: laboratory animal allergens on hair-covering caps and in mattress dust of laboratory animal workers.

BACKGROUND Family members of laboratory animal workers are at risk of developing allergy to laboratory animals. Little is known about the spreading of laboratory animal allergens outside the animal facilities. OBJECTIVE To assess the presence of laboratory animal allergens in dust collected from mattresses of laboratory animal workers and unexposed controls. METHODS Mouse and rat urinary pr...

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Health surveillance of workers exposed to laboratory animal allergens.

BACKGROUND Laboratory animal allergy (LAA) remains prevalent among workers exposed to laboratory animals. Pre-placement and health surveillance procedures vary between different employers. AIMS To determine evidence-based strategies for pre-placement and periodic health assessments for workers exposed to laboratory animals. METHODS Literature was searched systematically using Medline and EM...

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Detection of workers sensitised to high molecular weight allergens: a diagnostic study in laboratory animal workers.

OBJECTIVES To determine whether results from questionnaires, exposure measurements, and laboratory tests, commonly used in occupational health practice, can predict the presence or absence of sensitisation in workers exposed to high molecular weight (HMW) allergens. The study aims to develop and validate a diagnostic rule to predict sensitisation in laboratory animal workers. The main reason fo...

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ژورنال

عنوان ژورنال: ILAR Journal

سال: 2001

ISSN: 1084-2020

DOI: 10.1093/ilar.42.1.12